The heart revolution : the extraordinary discovery that finally laid the cholesterol myth to rest by McCully Kilmer S & McCully Martha

Author:McCully, Kilmer S & McCully, Martha
Language: eng
Format: epub
Tags: Heart, Homocysteine, Vitamin B complex, Vitamin B complex, Vitamin B complex in human nutrition, Heart Diseases, Homocysteine, Vitamin B Complex
Publisher: New York, NY : Perennial
Published: 2000-02-11T16:00:00+00:00

But methotrexate interferes with folic acid in the body, and so homocysteine levels rise. So far, its benefits in treating cancer have greatly outweighed the risk of high homocysteine's damaging arteries, especially since children are at a low risk of arteriosclerosis anyway because of their generally low homocysteine levels.

Laughing gas (nitrous oxide) is another drug that affects homocysteine in the blood. This gas causes blood homocysteine to rise quickly because it interferes with vitamin B12 within cells and tissues. The effect is temporary, and therefore it probably damages arteries only minimally. Of course, we don't know what happens to dentists and anesthesiologists who are exposed to low levels of the gas more frequently. A recent experiment showed that pigs exposed to nitrous oxide had not only high homocysteine levels but significant damage to their hearts. Next time you're at the dentist. Novocain might be the better choice. However, if you're allergic to Novocain or you're at high risk of heart disease, it may be worth supplementing your diet with B vitamins during prolonged dental work if nitrous oxide is being used for anesthesia.

Azaribine, a toxic drug used to fight certain cancers, also causes homocysteine to rise. Because of its extreme toxicity, the drug was not widely used after its discovery in the 1950s. But in the 1970s azaribine was given to suppress cell growth in patients with refractory psoriasis, a chronic skin disease usually treated with coal tar and ultraviolet light. Within a few years patients taking the drug for psoriasis experienced heart attack, stroke, and thrombosis. It was then determined that azaribine prevented B6 from acting in the body, and homocysteine levels shot through the roof, as did vascular disease. For this reason, in 1977, the FDA recalled azaribine

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